Myelodysplastic syndromes (MDS): prognostic factors and scoring systems

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Prognostic factors in myelodysplastic syndromes.

UNLABELLED BACKGROUND Myelodysplastic syndromes (MDS) are clonal disorders of hematopoietic stem cell and are characterized by ineffective hematopoiesis with normo- or hyper cellular bone marrow and cytopenia(s).The natural evolution of the disease consists of bone marrow failure (leading to infectious and hemorrhagic episodes or anemia related complications) and transformation to acute myel...

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Application of the International Prognostic Scoring System for myelodysplastic syndromes.

BACKGROUND In March 1997 an international workshop introduced a new International Prognostic Scoring System (IPSS) for MDS. The goal of the present study was to apply the IPSS to a large group of MDS patients from one centre and to compare it to the FAB-classification. PATIENTS One hundred eighty-four MDS patients were included on the basis of similar criteria as used by the workshop but some...

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MYELOID NEOPLASIA Revised International Prognostic Scoring System for Myelodysplastic Syndromes

Peter L. Greenberg,1 Heinz Tuechler,2 Julie Schanz,3 Guillermo Sanz,4 Guillermo Garcia-Manero,5 Francesc Solé,6 John M. Bennett,7 David Bowen,8 Pierre Fenaux,9 Francois Dreyfus,10 Hagop Kantarjian,5 Andrea Kuendgen,11 Alessandro Levis,12 Luca Malcovati,13 Mario Cazzola,13 Jaroslav Cermak,14 Christa Fonatsch,15 Michelle M. Le Beau,16 Marilyn L. Slovak,17 Otto Krieger,18 Michael Luebbert,19 Jaros...

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[Revised international prognostic scoring system (IPSS-R) for myelodysplastic syndromes].

Peter L. Greenberg, Heinz Tuechler, Julie Schanz, Guillermo Sanz, Guillermo GarciaManero, Francesc Solé, John M. Bennett, David Bowen, Pierre Fenaux, Francois Dreyfus, Hagop Kantarjian, Andrea Kuendgen, Alessandro Levis, Luca Malcovati, Mario Cazzola, Jaroslav Cermak, Christa Fonatsch, Michelle M. Le Beau, Marilyn L. Slovak, Otto Krieger, Michael Luebbert, Jaroslaw Maciejewski, Silvia M.M. Maga...

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Comparison of Myelodysplastic Syndrome Prognostic Scoring Systems

OBJECTIVE Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disease. Patients are at risk of developing cytopenias or progression to acute myeloid leukemia. Different classifications and prognostic scoring systems have been developed. The aim of this study was to compare the different prognostic scoring systems. MATERIALS AND METHODS One hundred and one patients who were diag...

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ژورنال

عنوان ژورنال: Sao Paulo Medical Journal

سال: 1997

ISSN: 1516-3180

DOI: 10.1590/s1516-31801997000500005